Notably, incubation of tumor cells with CAF conditioned medium alone also resulted in an upregulation of HMGCS2 and AKR1C3 suggesting a paracrine communication between tumor epithelial cells and CAFs lasix in usa f Western blot of SOX9 protein in cytoplasmic and nuclear fractions from MCF 7 TAMR cells treated with DMSO or HDAC4 HDAC5 inhibitor LMK 235 12 nM