cialis dosage Of the 745 papers initially retrieved online PRISMA flow diagram, we included 74 randomized trials comparing generic vs brand name drugs against cardiovascular diseases 9 13, 15 40, 42, 43, 53 56, 61 96 53 trials evaluated at least one efficacy outcome overall sample 3051, 32 trials measured mild or moderate adverse events n 2407, and 52 reported on serious adverse events n 2952