Programmed cell death receptor ligand 1 PD L1 inhibitors Atezolizumab, avelumab and durvalumab PD L1 is on tumor cells PEARL PD 1 and PD L1 can get delayed reactions, up to months and years Cytotoxic T lymphocyte associated antigen 4 CTLA 4 Ipilimumab and tremelimumab in development Side effects are due to immunologic enhancement and include dermatologic, rheumatologic, gastrointestinal, hepatic, endocrinologic Treatment includes immunosuppression, dose modification and cessation of therapy Reactions to checkpoint inhibitors Site of reaction Type of reaction Cutaneous
clomid and nolvadex for pct I lost my fallopian tube and along with it, the pregnancy