what is stromectol The clearance of avibactam was significantly decreased in subjects with mild CrCl greater than 50 to 80 mL min, n 6, moderate CrCl 30 to less than or equal to 50 mL min, n 6, and severe CrCl 30 mL min or less, not requiring hemodialysis; n 6 renal impairment compared to healthy subjects with normal renal function CrCl greater than 80 mL min, n 6 following administration of a single 100 mg intravenous dose of avibactam